Additive effects of coexisting respiratory comorbidities on overall or respiratory mortality in patients with asthma: a national cohort study

Autor: Yoomi Yeo, Hyun Lee, Jiin Ryu, Sung Jun Chung, Tai Sun Park, Dong Won Park, Sang-Heon Kim, Tae Hyung Kim, Jang Won Sohn, Ho Joo Yoon, Kyung Hoon Min, Ji-Yong Moon
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-022-12103-w
Popis: Abstract Asthmatic patients are generally considered to have an increased risk of mortality compared with subjects without asthma. However, this issue has been less evaluated using nationally representative data. Moreover, it is unclear whether respiratory comorbidities other than chronic obstructive pulmonary disease (COPD) are associated with increased mortality in asthmatic patients compared with subjects without. Using a nationally representative sample database, we performed a retrospective cohort study of patients with asthma and age-sex-matched control cohort. We estimated the hazard ratio (HR) and stratified the asthma cohort based on respiratory comorbidities. During a median 8.9-year follow-up, the overall mortality rate was higher in the asthma cohort than in the control cohort (p
Databáze: Directory of Open Access Journals
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