25-Hydroxyl Vitamin D Deficiency in Nasal Polyposis
| Autor: | Ankur Kumar Chandrakar, Arun Alexander, Medha R., Kalaiselvi Rajendiran, Karthikeyan Ramasamy |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | International Archives of Otorhinolaryngology, Vol 24, Iss 03, Pp e308-e312 (2020) |
| Druh dokumentu: | article |
| ISSN: | 1809-9777 1809-4864 |
| DOI: | 10.1055/s-0039-3399541 |
| Popis: | Introduction Vitamin D is known to have immunomodulatory functions and has action on chronic inflammatory processes, such as nasal polyposis. Objective The present study assessed the levels of 25-hydroxy vitamin D and high-sensitivity C-reactive protein (hs-CRP) in patients with nasal polyposis, as compared with healthy control subjects, and identified their association with disease severity in nasal polyposis. It further assessed the levels of 25-hydroxyl vitamin D and hs-CRP in patients with nasal polyposis and atopy and compared it with patients with nasal polyposis without atopy. Methods This was a cross-sectional study involving 2 groups: 80 patients with nasal polyposis and 80 healthy subjects. In patients with nasal polyposis, the disease severity is assessed by the sino-nasal outcome test (SNOT20) and by the Lund & Mackay staging system. Levels of 25-hydroxy vitamin D and hs-CRP were measured by enzyme-linked immunosorbent assay (ELISA). Result The mean 25-hydroxyl vitamin D levels (ng/ml) was 12.01 ± 7.29 for cases and 22.87 ± 14.95 for controls, with p |
| Databáze: | Directory of Open Access Journals |
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