Síntese de regioisômeros quirais a partir de D-manitol: obtenção de uma mistura de álcoois acetilênicos Synthesis of chirals regioisomers from D-mannitol: obtainment of a acetylenic alcohols mixture
| Autor: | Antônia Maria das Graças Lopes Citó, Bruno Quirino Araújo, José Arimatéia Dantas Lopes, Aderbal Farias Magalhães, Eva Gonçalves Magalhães |
|---|---|
| Jazyk: | English<br />Spanish; Castilian<br />Portuguese |
| Rok vydání: | 2009 |
| Předmět: | |
| Zdroj: | Química Nova, Vol 32, Iss 9, Pp 2355-2359 (2009) |
| Druh dokumentu: | article |
| ISSN: | 0100-4042 1678-7064 |
| DOI: | 10.1590/S0100-40422009000900023 |
| Popis: | The synthesis of chiral acetylenic regioisomers was described by using an appropriate intermediate such as isopropylidene glycerol, a synthon widely used in the enantioselective syntheses. This intermediate was prepared from D-mannitol. The nine obtained compounds have been characterized by their respective spectral data. The mixture of chiral acetylenic alcohols showed activity against Escherichia coli when tested through the monitoring of CO2 released during microbial respiration by using a conductimetric system. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|