Comparison of anti-Müllerian hormone and antral follicle count in the prediction of ovarian response: a systematic review and meta-analysis

Autor: Yang Liu, Zhengmei Pan, Yanzhi Wu, Jiamei Song, Jingsi Chen
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Ovarian Research, Vol 16, Iss 1, Pp 1-11 (2023)
Druh dokumentu: article
ISSN: 1757-2215
DOI: 10.1186/s13048-023-01202-5
Popis: Abstract Background Increasingly studies reported that the Anti-Müllerian hormone (AMH) seems to be a promising and reliable marker of functional ovarian follicle reserve, even better than the AFC test. Our study aimed to conduct a meta-analysis to assess the predictive value of AMH and AFC for predicting poor or high response in IVF treatment. An electronic search was conducted, and the following databases were used: PubMed, EMBASE, and the Cochrane Library (up to 7 May 2022). The bivariate regression model was used to calculate the pooled sensitivity, specificity, and area under the receiver operator characteristic (ROC) curve. Subgroup analyses and meta-regression also were used in the presented study. Overall performance was assessed by estimating pooled ROC curves between AMH and AFC. Results Forty-two studies were eligible for this meta-analysis. Comparison of the summary estimates for the prediction of poor or high response showed significant difference in performance for AMH compared with AFC [poor (sensitivity: 0.80 vs 0.74, P
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