Comparing the Efficiency of Propofol-Ketamine Combination and Propofol-Fentanyl on Recovery Time in Colonoscopy: A Double Blind Randomized Controlled Clinical Trial
| Autor: | Mohammad Esmaeili, Ghasem Yousefinia Pasha, Ebrahim Alijanpour, Mohamad Taghi Hamidian, Khadijeh Ezoji, Shahram Seyfi |
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| Jazyk: | English<br />Persian |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Journal of Mazandaran University of Medical Sciences, Vol 32, Iss 214, Pp 113-123 (2022) |
| Druh dokumentu: | article |
| ISSN: | 1735-9260 1735-9279 |
| Popis: | Background and purpose: Appropriate drug regimen during colonoscopy is one of the matters of concern in anesthesia. This study was conducted to compare the efficacy of propofol-ketamine combination and propofol-fentanyl in colonoscopy. Materials and methods: In a single-blind randomized clinical trial, 200 patients aged 18-60 years candidate for colonoscopy, were randomly allocated into two groups to receive either fentanyl-propofol (PF) or ketamine-propofol (PK) using block randomization. Recovery time (end of injection until Steward Score was 6) as the primary outcome and vital signs, complications, total dose of propofol, and satisfaction of the doctor performing the colonoscopy as secondary consequence were compared between the two groups. Results: Recovery time was 2.97 ± 0.89 min in the fentanyl-propofol group and 8.84 ± 1.73 min in ketamine-propofol group (P |
| Databáze: | Directory of Open Access Journals |
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