Accuracy and limitations of preoperative assessment of longitudinal spread of perihilar cholangiocarcinoma

Autor: Hikaru Hayashi, Akira Shimizu, Koji Kubota, Tsuyoshi Notake, Hitoshi Masuo, Takahiro Yoshizawa, Kiyotaka Hosoda, Hiroki Sakai, Koya Yasukawa, Yuji Soejima
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Asian Journal of Surgery, Vol 46, Iss 11, Pp 4743-4748 (2023)
Druh dokumentu: article
ISSN: 1015-9584
DOI: 10.1016/j.asjsur.2023.03.166
Popis: Objective: Although surgical resection offers the only chance of cure of perihilar cholangiocarcinoma and R1 resection has a poor prognosis, there is no consensus on optimal preoperative assessment of its longitudinal spread. We aimed to establish the optimal means of achieving this goal. Methods: This was a retrospective, single-center study of 61 patients who had undergone multi-detector row computed tomography, endoscopic retrograde cholangiography, intraductal ultrasonography, and mapping biopsy prior to resection of perihilar cholangiocarcinomas in our institute from January 2010 and December 2021. Results: The most accurate single methods for assessing longitudinal spread were intraductal ultrasonography and mapping biopsy (both 72.1%). A combination of all four assessment methods was accurate in 51 (83.6%) of our patients. Independent risk factors for inaccuracy were Bismuth–Corlette Type IV and high histologic-grade tumors. The R0 resection rate was higher with accurate than inaccurate assessments (90.2% vs. 30.0%, P
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