Synthesis of new triazole derivatives and their potential applications for removal of heavy metals from aqueous solution and antibacterial activities

Autor:	Chunyun Xu, Na Yang, Haichun Yu, Xiaojing Wang
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	1 2 4-triazole derivatives antibacterial activity anti biofilm anti inflammatory metal ion detection Chemistry QD1-999
Zdroj:	Frontiers in Chemistry, Vol 12 (2024)
Druh dokumentu:	article
ISSN:	2296-2646
DOI:	10.3389/fchem.2024.1473097
Popis:	In this paper, triazole derivatives were prepared by a three-step mild reaction using carbon disulfide as starting material. In face of microbial threats, we found that compound 3-cyclopropyl-[1,2,4]triazolo [3,4-b][1,3,4]thiadiazole-6-thiol (C2) has good antibacterial activity, inhibition and clearance ability against biofilms, low hemolytic activity and toxicity, good anti-inflammatory activity. At the same time, we found that B and C series compounds have good metal ion scavenging ability, with removal rates of C series ranging from 47% to 67% and B series ranging from 67% to 87%.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/f3a9477aa49d4f53b4e2845073f6c4b9 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.