| Autor: |
Amina A. Mahdy, Hala A. Raafat, Hussein S. El-Fishawy, Tamer A. Gheita |
| Jazyk: |
angličtina |
| Rok vydání: |
2014 |
| Předmět: |
|
| Zdroj: |
Bulletin of Faculty of Pharmacy Cairo University, Vol 52, Iss 1, Pp 37-43 (2014) |
| Druh dokumentu: |
article |
| ISSN: |
1110-0931 |
| DOI: |
10.1016/j.bfopcu.2014.01.002 |
| Popis: |
Objective: To assess the serum B-cell activating factor belonging to the tumor necrosis factor family (BAFF) level in rheumatoid arthritis (RA) patients in view of different treatment regimens received and evaluate its relation with disease activity. Patients and methods: Ninety female RA patients were included. Sixty were on disease modifying anti-rheumatic drugs (DMARDs); 34 on hydroxychloroquine (HCQ) plus methotrexate (MTX), 26 on leflunomide (LFN) plus MTX and 30 newly diagnosed cases not yet on any treatment. Thirty age and gender matched healthy subjects served as controls. Full history taking, clinical examination and relevant laboratory investigations were performed. Disease activity score, in 28 joints (DAS-28), was calculated. Results: Serum BAFF level was significantly higher in patients (1.82 ± 0.91 ng/ml) compared to control (0.71 ± 0.33 ng/ml; p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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