Toward Clinically Compatible Phase-Contrast Mammography.

Autor: Kai Scherer, Konstantin Willer, Lukas Gromann, Lorenz Birnbacher, Eva Braig, Susanne Grandl, Anikó Sztrókay-Gaul, Julia Herzen, Doris Mayr, Karin Hellerhoff, Franz Pfeiffer
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: PLoS ONE, Vol 10, Iss 6, p e0130776 (2015)
Druh dokumentu: article
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0130776
Popis: Phase-contrast mammography using laboratory X-ray sources is a promising approach to overcome the relatively low sensitivity and specificity of clinical, absorption-based screening. Current research is mostly centered on identifying potential diagnostic benefits arising from phase-contrast and dark-field mammography and benchmarking the latter with conventional state-of-the-art imaging methods. So far, little effort has been made to adjust this novel imaging technique to clinical needs. In this article, we address the key points for a successful implementation to a clinical routine in the near future and present the very first dose-compatible and rapid scan-time phase-contrast mammograms of both a freshly dissected, cancer-bearing mastectomy specimen and a mammographic accreditation phantom.
Databáze: Directory of Open Access Journals