Synthesis and characterization of naringin functionalized nano-hydroxyapatite for bone tissue engineering

Autor: M Prem B. Rajula, Vivek Narayanan, G Devanand Venkatasubbu, D Prema, P L Ravishankar, Rekha Mani
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Pharmacy and Bioallied Sciences, Vol 15, Iss 5, Pp 372-376 (2023)
Druh dokumentu: article
ISSN: 0975-7406
DOI: 10.4103/jpbs.jpbs_626_22
Popis: Bone is a unique nanocomposite tissue composed of organic and inorganic materials. Bone grafting is a common surgical method used to improve bone regeneration in dentistry and orthopedic surgery. Because standard therapies have substantial drawbacks, nanomaterials provide alternative options for bone repair. Owing to its high bioactivity, osteoconductivity, biocompatibility, and topography that matches the architecture of real bone, hydroxyapatite nanoparticles (n-HA) are commonly used in bone treatment. We report here the synthesis and characterization of Naringin (NA) functionalized n-HA using HRTEM, FTIR, XRD, and UV-visible spectroscopy. The obtained results indicated that the n-HA can be functionalized with Naringin and they might be used as a bone regenerative material in medical and dental fields.
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