Synthesis of Novel bis-1,5-Disubstituted-1H-Tetrazoles by an Efficient Catalyst-Free Ugi-Azide Repetitive Process

Autor: Luís E. Cárdenas-Galindo, Alejandro Islas-Jácome, Karla M. Colmenero-Martínez, Antonio Martínez-Richa, Rocío Gámez-Montaño
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Molecules, Vol 20, Iss 1, Pp 1519-1526 (2015)
Druh dokumentu: article
ISSN: 1420-3049
DOI: 10.3390/molecules20011519
Popis: A series of five novel bis-1,5-disubstituted-1H-tetrazoles (bis-1,5-DS-1H-T) were quickly prepared by a catalyst-free Ugi-azide repetitive process from easily accessible starting materials in excellent yields, either at room temperature (88%–95%) or using mild MW-heating conditions (80%–91%). These molecules may have a wide range of applications, such as chelating agents, organocatalysts and luminescent materials, and mainly as bioactive compounds.
Databáze: Directory of Open Access Journals