Could tumour volume and major and minor axis based on CTA statistical anatomy improve the pre‐operative T‐stage in oesophageal cancer?

Autor: Runyuan Wang, Xiaoqin Zhang, Wei Wu, Jinfeng Ma, Jincheng Chen, Zhu Zhang, Liqun Liu, Shanshan Xu, Ximei Cao, Yi Wu, Huilin Cui
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Cancer Medicine, Vol 12, Iss 13, Pp 14037-14051 (2023)
Druh dokumentu: article
ISSN: 2045-7634
DOI: 10.1002/cam4.6051
Popis: Abstract Objectives To statistically study the 3D shape of oesophageal cancer (EC) and its spatial relationships based on computed tomography angiography (CTA) 3D reconstruction, to determine its relationship with T‐stages, and to create an optimal T‐stage diagnosis protocol based on CTA calculation. Methods Pre‐operative CTA images of 155 patients with EC were retrospectively collected and divided into four groups: T1–T4. We used Amira software to segment and 3D reconstruct the EC, oesophagus, aorta, pericardium and peripheral lymph nodes and measured their surface area, volume, major axis, minor axis, longitudinal length, roughness and relationship to the aorta of the EC. One‐way ANOVA, independent sample t‐test, ROC, etc., were performed and critical values between different T‐stages were calculated. We also invited two radiologists to evaluate the measurements. Results There were no significant differences in EC longitudinal length, roughness score and relationship with the aorta between the different T‐stages of EC. There were significant differences in EC surface area, EC volume and mean major and minor axis among the different T‐stages. The volumes of the T1–T4 tumours were 12,934.36 ± 7739.25, 23,095.27 ± 14,975.67, 37,577.98 ± 36,085.64 and 58,579.25 ± 41,073.96 mm3 separately (p
Databáze: Directory of Open Access Journals
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