| Autor: |
Giscard F. Komoyo, Brice M. Yambiyo, Alexandre Manirakiza, Jean C. Gody, Claude P. Muller, Judith M. Hübschen, Emmanuel Nakoune, Chantal J. Snoeck |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Health Science Reports, Vol 4, Iss 2, Pp n/a-n/a (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2398-8835 |
| DOI: |
10.1002/hsr2.298 |
| Popis: |
Abstract Background and aims Respiratory syncytial virus (RSV) is one of the main viral pathogens causing acute respiratory infections in children under 5 years of age but has seldom been studied in Central African Republic (CAF). Taking advantage of the national influenza surveillance network in CAF, this study aimed at providing the first insights into RSV prevalence and seasonality over 4 years of surveillance and the clinical manifestations of RSV in this population in CAF. Methods A total of 3903 children under 5 years matching the influenza‐like illness (ILI, 68.5%) or severe acute respiratory infection (SARI, 31.5%) case definitions were recruited from January 2015 to December 2018. The presence of RSV viral RNA in nasopharyngeal samples was assessed by RT‐PCR, followed by RSV‐A and RSV‐B typing and Sanger sequencing on a subset of samples. Phylogenetic analyses were carried on partial G protein sequences. Associations between RSV and demographic or clinical manifestations were investigated by statistical analyses. Results RSV prevalence was significantly higher in infants |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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