Does influenza vaccination status change physician ordering patterns for respiratory viral panels? Inspection for selection bias

Autor: G.K. Balasubramani, Sean Saul, Mary Patricia Nowalk, Donald B. Middleton, Jill M. Ferdinands, Richard K. Zimmerman
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Human Vaccines & Immunotherapeutics, Vol 15, Iss 1, Pp 91-96 (2019)
Druh dokumentu: article
ISSN: 2164-5515
2164-554X
21645515
DOI: 10.1080/21645515.2018.1514226
Popis: Purpose: Hospitalized patients with an acute respiratory illness (ARI) were compared to determine if demographic characteristics, timing or influenza vaccination biased who received clinical respiratory viral panel (RVP) testing. Methods: 171 enrollees in an influenza vaccine effectiveness study and a sample of non-enrollees (N = 1029) admitted to a community hospital with ARI during December 2015 through April 2016 comprised the study sample. Those who received clinical RVP testing (n = 292) were compared to those who did not by age, sex, influenza vaccination status, and period (pre-peak influenza season vs. peak/post peak influenza season), using Chi square- and t-tests, and logistic regression. Results: Mean age of participants was 70 years, 58% was female and 45% had been vaccinated against influenza in the 2015–2016 season. Those with clinical RVP testing were significantly younger (67 years) than those without RVP (71 years; P
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