Pseudomonas aeruginosa in the ICU: prevalence, resistance profile, and antimicrobial consumption

Autor: Ághata Cardoso da Silva Ribeiro, Márcia Terezinha Lonardoni Crozatti, Adilson Aderito da Silva, Rodrigo Spineli Macedo, Antonia Maria de Oliveira Machado, Antonio Távora de Albuquerque Silva
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Revista da Sociedade Brasileira de Medicina Tropical, Vol 53 (2019)
Druh dokumentu: article
ISSN: 1678-9849
0037-8682
DOI: 10.1590/0037-8682-0498-2018
Popis: Abstract INTRODUCTION: Pseudomonas aeruginosa is one of the main pathogens causing infection in intensive care units (ICUs) and usually presents antimicrobial resistance. METHODS: Data were obtained from ICUs between 2010 and 2013. RESULTS: P. aeruginosa had a prevalence of 14.5% of which 48.7% were multidrug resistant. We observed increasing resistance to carbapenems and polymyxin B and growing consumption of aminoglycosides, meropenem, ceftazidime, and polymyxin B. The regression impact between resistance and consumption was significant with respect to amikacin, imipenem, meropenem, and polymyxin B. CONCLUSIONS: Monitoring antimicrobial consumption and resistant microorganisms should be reinforced to combat antimicrobial- and multi-drug resistance.
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