Correlation between Human Herpes virus 8 (HHV8-) and Plasma Cell Myeloma: a Systematic Review
| Autor: | Mohammad Hadi Sadeghian, Zahra Rezaei Dezaki, Seyyede Fatemeh Shams, Sepideh Shakeri |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Reviews in Clinical Medicine, Vol 5, Iss 3, Pp 95-100 (2018) |
| Druh dokumentu: | article |
| ISSN: | 2345-6256 2345-6892 |
| DOI: | 10.22038/rcm.2018.32149.1235 |
| Popis: | Introduction: Plasma cell myeloma is the distortion of differentiated B lymphocytes which is associated with uncontrolled proliferation of plasma cells in bone marrow. Some studies propound a role for HHV-8 virus in pathogenesis of plasma cell myeloma. Yet the findings are inconsistent. In this article we reviewed the literatures to determine the HHV-8 virus role in plasma cell myeloma pathogenesis.Methods: In this systematic review, scientific databanks including PubMed, Scopus, Embase, ISI, and Google scholar were searched. The search was based on the subsequent keywords and medical terms in title; different combinations of keywords were used, they were compatible with MeSH terms.Result: Four articles declared that there is no link between the HHV-8 and the pathogenesis of plasma cell myeloma; while five reported a connection between the virus and myeloma, arguing that virus infection will lead to disease progression.Conclusion: There are differences between the results of the studies. It is required to do further researches about the association of HHV-8 and plasma cell myeloma. |
| Databáze: | Directory of Open Access Journals |
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