Comparison of malignancy and spatial distribution between latent and clinical prostate cancer: an 8-year biopsy study

Autor: Liang Zhen, Zhou Zhien, Huang Hanzi, Wu Xingcheng, Xiao Yu, Wang Wenze, Zuo Yuzhi, Chen Yuliang, Zhou Yi, Yan Weigang
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: European Journal of Medical Research, Vol 27, Iss 1, Pp 1-8 (2022)
Druh dokumentu: article
ISSN: 2047-783X
DOI: 10.1186/s40001-022-00801-0
Popis: Abstract Background Current prostate cancer (PCa) screening may detect nonprogressive lesion, leading to overdiagnosis and overtreatment. The purpose of the present study is to investigate whether the tumor pathological origin of latent prostate cancer (lPCa) and clinical prostate cancer (cPCa) are consistent, and to verify the current clinically significant prostate cancer criteria. Methods Prostate specimens were obtained from postmortem autopsy between 2014 and 2021 and patients who went through radical prostatectomy from 2013 to 2021. The pathological characteristics and spatial distribution of the lPCa group and cPCa group were compared and analyzed through SPSS software with P
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