Cyclodextrin-Based Contrast Agents for Medical Imaging

Autor:	Yurii Shepelytskyi, Camryn J. Newman, Vira Grynko, Lauren E. Seveney, Brenton DeBoef, Francis T. Hane, Mitchell S. Albert
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	medical imaging contrast agents α-cyclodextrin β-cyclodextrin γ-cyclodextrin MRI Organic chemistry QD241-441
Zdroj:	Molecules, Vol 25, Iss 23, p 5576 (2020)
Druh dokumentu:	article
ISSN:	1420-3049
DOI:	10.3390/molecules25235576
Popis:	Cyclodextrins (CDs) are naturally occurring cyclic oligosaccharides consisting of multiple glucose subunits. CDs are widely used in host–guest chemistry and biochemistry due to their structural advantages, biocompatibility, and ability to form inclusion complexes. Recently, CDs have become of high interest in the field of medical imaging as a potential scaffold for the development of a large variety of the contrast agents suitable for magnetic resonance imaging, ultrasound imaging, photoacoustic imaging, positron emission tomography, single photon emission computed tomography, and computed tomography. The aim of this review is to summarize and highlight the achievements in the field of cyclodextrin-based contrast agents for medical imaging.
Databáze:	Directory of Open Access Journals
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