Chiron approach and the [4 + 2] Diels-Alder cycloaddition of 2-pyrones for the synthesis of cis-(-)-aminoindan-2-ol

Autor: Arturo de la Rosa-Barrales, J. Alvano Pérez-Bautista, Silvano Cruz-Gregorio, R. Luisa Meza-León, Leticia Quintero, Omar Cortezano-Arellano, Fernando Sartillo-Piscil
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Results in Chemistry, Vol 3, Iss , Pp 100174- (2021)
Druh dokumentu: article
ISSN: 2211-7156
DOI: 10.1016/j.rechem.2021.100174
Popis: A cascade Diels-Alder reaction coupled with an oxidative aromatization reaction was developed and applied to a chiral 2-pyrone for the synthesis of the relevant chiral synthon/chiral auxiliary (-)-cis-aminoindan-2-ol. Chirality and optical purity were provided by the privileged chiron 7,3-LXF.
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