The Importance of Using SOX10 for Exact Diagnosis of Desmoplastic Melanoma

Autor: Adamicova K, Fetisovova Z, Bobrovska M, Homola I
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Acta Medica Martiniana, Vol 19, Iss 3, Pp 111-116 (2019)
Druh dokumentu: article
ISSN: 1338-4139
DOI: 10.2478/acm-2019-0015
Popis: Desmoplastic malignant melanoma is a rare variant of spindle cell melanoma commonly seen in older adults on sun-exposed areas. It accounts for 1–4 % of all cases of cutaneous melanoma. The common location of the desmoplastic melanoma is the head and neck region, whereasother sites are less common. A 45-year-old male presented with an proliferative growth on nose, after a trauma that was diagnosed as tumor. Histopathological examination with the help of wide panel of immunohistochemical methods and with emphasis on SOX10, was, after a broad diferential diagnosis concluded as a desmoplastic melanoma.
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