Unexpected Occurrence of Plasmid-Mediated Quinolone Resistance Determinants in Environmental Aeromonas spp.

Autor:	Vincent Cattoir, Laurent Poirel, Camille Aubert, Claude-James Soussy, Patrice Nordmann
Jazyk:	angličtina
Rok vydání:	2008
Předmět:	Qnr QnrS antibiotic resistance reservoir Aeromonas punctata subsp. punctata Aeromonas media Medicine Infectious and parasitic diseases RC109-216
Zdroj:	Emerging Infectious Diseases, Vol 14, Iss 2, Pp 231-237 (2008)
Druh dokumentu:	article
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid1402.070677
Popis:	We searched for plasmid-mediated quinolone resistance determinants of the Qnr type in several water samples collected at diverse locations from the Seine River (Paris, France). The qnrS2 genes were identified from Aeromonas punctata subsp. punctata and A. media. The qnrS2 gene was located on IncU-type plasmids in both isolates, which resulted in increased MIC values of quinolones and fluoroquinolones, once they were transferred into Escherichia coli. The qnrS2 gene identified in A. punctata was part of novel genetic structure corresponding to a mobile insertion cassette element. This identification of plasmid-mediated qnr genes outside Enterobacteriaceae underlines a possible diffusion of those resistance determinants within gram-negative rods.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/f316bdb196044d80ab831fff8930e655 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF