A case of disseminated carcinomatosis of the bone marrow from gastric cancer developing rapidly after a gastrectomy

Autor: Shunsuke Sato, Yuji Ishibashi, Koichiro Kawasaki, Ryoto Yamazaki, Fumihiko Hatao, Yasuhiro Morita, Kazuhiro Imamura
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Surgical Case Reports, Vol 7, Iss 1, Pp 1-6 (2021)
Druh dokumentu: article
ISSN: 2198-7793
31312837
DOI: 10.1186/s40792-021-01135-5
Popis: Abstract Background Disseminated carcinomatosis of the bone marrow (DCBM) is often associated with disseminated intravascular coagulation (DIC) and a poor prognosis. Moreover, the timing of the diagnosis varies. We presented herein the first report of a case of DCBM from gastric cancer that developed rapidly after a gastrectomy. Case presentation A 42-year-old male patient was referred to us for gastric cancer. Preoperative laboratory tests were normal. Abdominal computed tomography (CT) revealed no obvious bone metastasis, and he underwent a laparoscopic distal gastrectomy. On postoperative day (POD) 1, laboratory data indicated severe thrombocytopenia. Postoperative bleeding requiring reoperation was found. Afterwards, he complained of lower back pain. His ALP and LDH gradually became elevated. On POD 8, DIC was diagnosed. CT and bone scintigraphy showed multiple, widespread bone metastases. Based on these findings, DCBM from gastric cancer was diagnosed. Systemic chemotherapy was started on POD 12. The DIC subsided during the first course, and he was discharged on POD 21. The patient died of tumor progression 7 months later. Conclusion When thrombocytopenia is observed immediately after a gastrectomy for gastric cancer, the possibility of DCBM should be considered.
Databáze: Directory of Open Access Journals
Externí odkaz: