| Autor: |
Abdel-sadek Hamed Al-aarag, Mohammad Hussein Kamel, Eman Ramadan Abdelgawad, Shaimaa Magdy Abo-Youssef, Hany Hussein Moussa, Marwa Elsayed Elnaggar, Rasha Mohammad Hendy, Koot Ahmad Diab |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
BMC Pulmonary Medicine, Vol 19, Iss 1, Pp 1-8 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
1471-2466 |
| DOI: |
10.1186/s12890-019-0874-y |
| Popis: |
Abstract Background Tuberculous pleurisy and malignancy are two of the most common causes of pleural effusion. IL-33 is expressed in the epithelial lining and endothelial cells and is released after cell damage; it is proposed to have an essential role in sensing damage in various infectious and inflammatory diseases. This work aimed to determine the diagnostic role of IL-33 in pleural effusions. Methods One hundred seventeen patients with pleural effusions of different etiologies had a quantitative measurement of IL-33 in their pleural effusion and serum samples by ELISA technique. Results The concentrations of IL-33 (mean ± SD) in tuberculous pleural effusion (TPE) group (22.5 ± 0.90 ng/l) were significantly higher than that of malignant pleural effusion (MPE) group (14.6 ± 2.35 ng/l; P 0.05). The concentrations of IL-33 in the pleural effusions were significantly correlated to that of the serum concentrations in each group (TPE: r = 0.848, P = 1.4 with a sensitivity of 91.7% and specificity of 100% while for the determination of (MPE) was |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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