ENDOTHELIOPROTECTIVE AND CARDIOPROTECTIVE ACTIVITY OF SELECTIVE ARGINASE II INHIBITOR
Autor: | V. I. Yakushev, V. V. Gureev, M. V. Pokrovskii, M. V. Korokin, O. S. Gudyrev, T. G. Pokrovskaya, E. A. Beskhmelnitsyna, A. S. Litvinova, V. V. Elagin |
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Jazyk: | ruština |
Rok vydání: | 2015 |
Předmět: | |
Zdroj: | Кубанский научный медицинский вестник, Iss 3, Pp 139-142 (2015) |
Druh dokumentu: | article |
ISSN: | 1608-6228 2541-9544 |
Popis: | They researched endothelioprotective and cardioprotective activity of arginase II selective inhibitor (substance code ZB49-0010C) in model of L-NAME-induced deficit of nitric oxide. The results of studies of arginase II selective inhibitor (substance code ZB49-0010C) show the presence dose-dependent endothelioprotective and cardioprotective activity, the severity of which sincreases with increasing dose. |
Databáze: | Directory of Open Access Journals |
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