Ionic liquid mediated efficient synthesis of 2,4,5-triarylimidazoles via green economical multicomponent reaction

Autor: Ramesh A. Mokal, Suresh C. Jadhavar
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Current Chemistry Letters, Vol 13, Iss 3, Pp 483-490 (2024)
Druh dokumentu: article
ISSN: 1927-7296
1927-730X
DOI: 10.5267/j.ccl.2024.3.001
Popis: In the present work, a new protocol was developed for the synthesis of 2,4,5-triaryl imidazoles via three component condensation of aryl aldehyde, benzil and ammonium acetate in the presence of 1-butyl-3-methyl-imidazolium hexafluoro phosphate ([BMIM][PF6]) as a catalyst under reflux in ethanol. The present protocol has many beneficial advantages such as excellent yields, easy workup procedure, green catalyst and purification of the targeted molecules without the use of column chromatography which increases the green chemistry value of the present work.
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