| Autor: |
Wichaya Jaroonsakchai, Julajak Limsrivilai, Phutthaphorn Phaophu, Nichcha Subdee, Popchai Ngamskulrungroj, Nonthalee Pausawasdi, Phunchai Charatcharoenwitthaya, Supot Pongprasobchai |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Siriraj Medical Journal, Vol 76, Iss 4 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2228-8082 |
| Popis: |
Objective: Fecal calprotectin (FC) has an essential role in differentiating inflammatory diarrhea from functional diarrhea in an outpatient setting; however, its role in nosocomial diarrhea remains not well explored. Materials and Methods: This is a prospective observational study. We included adult inpatients with nosocomial diarrhea and categorized them into diarrhea likely (group A) and unlikely (group B) to have lesions in the colonic mucosa. Group A included infectious diarrhea such as Clostridium difficile and ischemic colitis. Group B comprised tube-feeding diarrhea, non-C. difficile antibiotic-associated diarrhea, and drug-induced diarrhea. The FC levels were compared between the two groups. Results: 135 patients were included, 45 in group A and 90 in group B. Median FC was 902 mg/kg (interquartile range [IQR] 549-2,175) of feces in group A, significantly higher than the median level of 377 mg/kg (IQR 141-664) of feces in group B (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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