The effects of Bifidobacterium animalis subsp. lactis and vitamin D on immunological response following vaccination in puppies

Autor: Gökhan Saridag, Songul Erdogan, Tahir Ozalp, Kerem Ural, Hasan Erdogan
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Macedonian Veterinary Review, Vol 46, Iss 2, Pp 199-206 (2023)
Druh dokumentu: article
ISSN: 1409-7621
1857-7415
DOI: 10.2478/macvetrev-2023-0025
Popis: This study aimed to determine the effects of oral application of Bifidobacterium animalis subsp. lactis and vitamin D on the immune response after vaccination in puppies. Crossbred dogs at the age of 55–65 days (n=21) of both sexes were grouped according to the application as follows: Group 1 - commercial polyvalent vaccine only (Vanguard 5L4, Zoetis); Group 2 - polyvalent vaccine and vitamin D; and Group 3 - polyvalent vaccine, B. animalis subsp. lactis, and vitamin D. The antibody titers, measured 3 weeks after the vaccination and after the 1st booster, demonstrated sufficient protective levels against the canine distemper virus but without significant difference between the groups when compare both values. No significant differences either, were observed in antibody titers against canine parvovirus after the initial vaccination. However, after the 1st booster, Group 2 samples showed significantly higher antibody titer value compared to the other groups (p
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