Supercritical fluid chromatography-mass spectrometry enables simultaneous measurement of all phosphoinositide regioisomers

Autor: Yuta Shimanaka, Keiko Matsumoto, Yuki Tanaka, Yuki Ishino, Shenwei Ni, Jun-Lin Guan, Hiroyuki Arai, Nozomu Kono
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Communications Chemistry, Vol 5, Iss 1, Pp 1-10 (2022)
Druh dokumentu: article
ISSN: 2399-3669
DOI: 10.1038/s42004-022-00676-6
Popis: Phosphoinositide (PIP) species play important roles in a number of cellular events, but the simultaneous quantification of individual PIP species remains challenging using conventional methods. Here, the authors report a supercritical fluid chromatography-mass spectrometry approach to simultaneous measure the molecular species of all seven PIP regioisomers.
Databáze: Directory of Open Access Journals
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