Development of Candelilla Wax Oleogels as a Medium of Controlled Release of Phosphorus in an In Vitro Model

Autor: Genaro Olmos-Oropeza, Mayra Aguilar-Zárate, María Zenaida Saavedra-Leos, Luis Gerardo Martínez-Juárez, Jorge Fernando Toro-Vazquez, Armando Sánchez-Macías, Laura Araceli López-Martínez
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Applied Sciences, Vol 11, Iss 9, p 3815 (2021)
Druh dokumentu: article
ISSN: 2076-3417
DOI: 10.3390/app11093815
Popis: Candelilla wax (CW) oleogels were developed as an alternative bolus material for delivering phosphorus into the rumen of goats. The systems were studied at three CW concentrations (10%, 15% and 20%) in vegetable oil. Each oleogel was added with a specific amount of calcium orthophosphate as a phosphorus source. The thermomechanical properties of the oleogels were characterized by DSC and rheology, and the viability of phosphorus delivery was evaluated using a laboratory model in two mediums (one aqueous and another with ruminal fluid). The results showed that the oleogels had a higher melting point (~52.8 °C) than the temperature of the ruminal environment and greater G′ values (1.6 × 106 Pa in 20% CW oleogel with phosphorus). Such characteristics guaranteed the integrity of the materials during the process in the model systems studied. It was demonstrated that when using the 20% CW oleogel, the phosphorus was slowly released for 84 h, completing a maximum of 83.3–98% of the total amount of phosphorus added to the bolus (in the aqueous and ruminal fluid models, respectively). These results enable us to propose this material as a delivery system for phosphorus supplementation in goats. Its effectivity in goats will be evaluated in future in vivo investigations.
Databáze: Directory of Open Access Journals