Antimicrobial activity of complete denture cleanser solutions based on sodium hypochlorite and Ricinus communis – a randomized clinical study

Autor: Marcela Moreira SALLES, Maurício Malheiros BADARÓ, Carolina Noronha Ferraz de ARRUDA, Vanessa Maria Fagundes LEITE, Cláudia Helena Lovato da SILVA, Evandro WATANABE, Viviane de Cássia OLIVEIRA, Helena de Freitas Oliveira PARANHOS
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Journal of Applied Oral Science, Vol 23, Iss 6, Pp 637-642 (2015)
Druh dokumentu: article
ISSN: 1678-7765
1678-7757
DOI: 10.1590/1678-775720150204
Popis: ABSTRACT To preserve oral health and to maintain the prosthetic devices, it is important not only to improve the properties of commonly known hygiene products, but also to investigate new materials with antimicrobial action. Objectives This study evaluated the antimicrobial activity of sodium hypochlorite (0.25% and 0.50%) and 10% Ricinus communis’ solutions against specific microorganisms. Material and Methods Sixty four maxillary complete denture wearers were instructed to brush their dentures three times a day and to soak them (20 min/day) in the solutions: SH1: 0.25% sodium hypochlorite; SH2: 0.5% sodium hypochlorite; RC: 10% R. communis oil; and C: 0.85% saline (control). The solutions were used for 7 days in a randomized sequence. Following each period of use, there was a 1-week washout period. Antimicrobial activity was determined by Colony Forming Units (CFU) counts of Streptococcus mutans, Candida spp., and gram-negative microorganisms. For collecting biofilm, the internal surface of maxillary dentures was brushed with saline solution, and biofilm suspension obtained. After dilutions (100 - 10-3), aliquots were seeded in Mitis salivarius, CHROMagar Candida®, and MacConkey agar for detecting S. mutans, Candida spp., or gram-negative microorganisms, respectively. After incubation, colonies were counted, and CFU/mL values were calculated. Then, transformation - log10 (CFU+1) - data were analyzed using the Friedman test (α=0.05). Results showed significant differences between the solutions (p
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