| Autor: |
Colette Lacabanne, Michel Spina, Alessandro Gandaglia, Mohammed Yousfi, Jean-Pierre Gardou, Nofel Merbahi, Jany Dandurand, Florian Delaunay, Valérie Samouillan |
| Jazyk: |
angličtina |
| Rok vydání: |
2011 |
| Předmět: |
|
| Zdroj: |
Journal of Functional Biomaterials, Vol 2, Iss 3, Pp 230-248 (2011) |
| Druh dokumentu: |
article |
| ISSN: |
2079-4983 |
| DOI: |
10.3390/jfb2030230 |
| Popis: |
In this paper we explore the ability of thermal analysis to check elastin and collagen integrity in different biomaterial applications. Differential Scanning Calorimetry (DSC) has been used to analyze the first and second order transitions of the biological macromolecules in the hydrated and dehydrated state. First, we report the characterization of control cardiovascular tissues such as pericardium, aortic wall and valvular leaflet. Their thermal properties are compared to pure elastin and pure collagen. Second, we present results obtained on two collagen rich tissues: pericardia with different chemical treatments and collagen with physical treatments. Finally, more complex cardiovascular tissues composed of elastin and collagen are analyzed and the effect of detergent treatment on the physical structure of collagen and elastin is brought to the fore. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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