Red shell‐ high risk normal tissue in stereotactic radiosurgery

Autor:	Jun Yang, Weihua Qi, Lei Wang, Qiuxia Lu, Liangfu Han, Brian Wang, Weisi Yan
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	biological equivalent dose normal tissue Red Shell stereotactic radiosurgery toxicity Medical physics. Medical radiology. Nuclear medicine R895-920 Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	Precision Radiation Oncology, Vol 7, Iss 4, Pp 273-277 (2023)
Druh dokumentu:	article
ISSN:	2398-7324 49999869
DOI:	10.1002/pro6.1218
Popis:	Abstract Due to the ablative nature of high prescription in Stereotactic Radiosurgery or stereotactic body radiation therapy (SRS/SBRT), the normal tissue surrounding the CTV receives the dose higher than tissue's dose constraint. A concept of Red Shell is proposed to define and quantify these tissue damaged in SBRT, using biological equivalent dose (BED) concept. The combination of biological factors and physics factors, including serial and parallel organ, dose gradient, dose distribution and fractionations, are further discussed to interpret the clinical meaning of Red Shell. This concept can also help planner to improve the optimization in planning process.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/f2aa26f8bd0e49999869562c8276deb1 Zobrazit plný text záznamu Plný text View record in DOAJ