Arrangement and symmetry of the fungal E3BP-containing core of the pyruvate dehydrogenase complex

Autor: B. O. Forsberg, S. Aibara, R. J. Howard, N. Mortezaei, E. Lindahl
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-020-18401-z
Popis: The pyruvate dehydrogenase complex (PDC) is a multienzyme complex connecting glycolysis to mitochondrial oxidation of pyruvate. Cryo-EM analysis of PDC from Neurospora crassa reveals localization of fungi-specific protein X (PX) and confirms that it functions like the mammalian E3BP, recruiting the E3 component of PDC.
Databáze: Directory of Open Access Journals