Detection of early cleavage embryos improves pregnancy and delivery rates of Day 3 embryo transfer during in vitro fertilization
| Autor: | Chun-I Lee, Tsung-Hsien Lee, Chun-Chia Huang, Hsiu-Hui Chen, Chung-Hsien Liu, Maw-Sheng Lee |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Taiwanese Journal of Obstetrics & Gynecology, Vol 55, Iss 4, Pp 558-562 (2016) |
| Druh dokumentu: | article |
| ISSN: | 1028-4559 64768872 |
| DOI: | 10.1016/j.tjog.2016.06.005 |
| Popis: | Objective: This study established a simple criterion for improving the pregnancy and delivery rates of Day 3 embryo transfer for in vitro fertilization (IVF) by assessing the early cleavage of two-cell stage embryos. Materials and Methods: In total, 258 cycle patients undergoing an IVF and Day 3 embryo transfer program were recruited. All cycles were divided into four groups containing viable Day 3 embryos and those (A) with distinct early cleavage (equal-sized blastomeres and ≤10% fragmentation: ECA grade); (B) with indistinct early cleavage (equal sized blastomeres, >2 blastomeres, or >10% fragmentation: ECB grade); (C) without early cleavage [no early cleavage (NEC grade)]; or (D) without early cleavage being assessed (control) at 25–27 after insemination. Results: The percentage of viable Day 3 embryos from ECA grade (75.1%, 507/675) was significantly higher than that from ECB grade (19.2%, 151/403) or NEC grade (27.1%, 127/469) embryos (p |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|