Associations of three thermogenic adipokines with metabolic syndrome in obese and non-obese populations from the China plateau: the China Multi-Ethnic Cohort

Autor: Yanjiao Wang, Juan Huang, Ying Qian, Rudan Hong, Jianzhong Yin, Zhimin Zhao, Dubo Zhong, Zhuohang Che, Yahui Xu, Qiong Meng
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: BMJ Open, Vol 13, Iss 7 (2023)
Druh dokumentu: article
ISSN: 2044-6055
DOI: 10.1136/bmjopen-2022-066789
Popis: Objectives High altitude exposure decreases the incidence of obesity and metabolic syndrome, but increases the expression of the thermogenic adipokines (leptin, fat cell fatty acid-binding protein (A-FABP) and visfatin). This study investigated the correlation of these adipokines with obesity and metabolic syndrome (MetS) in populations residing in a plateau-specific environment.Design Case–control study.Setting We cross-sectionally analysed data from the China Multi-Ethnic Cohort.Participants A total of 475 obese (OB, body mass index (BMI)≥28.0 kg/m2) plateau Han people and 475 age, sex and region-matched non-obese (NO, 18.5≤BMI
Databáze: Directory of Open Access Journals