Genome-wide association study of birth weight and pre-weaning body weight of crossbred pigs
| Autor: | KARTHIKEYAN A, AMIT KUMAR, RAJNI CHAUDHARY, AAMIR BASHIR WARA, AKANSHA SINGH, N R SAHOO, MOHD BAQIR, B P MISHRA |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Indian Journal of Animal Sciences, Vol 90, Iss 2 (2020) |
| Druh dokumentu: | article |
| ISSN: | 0367-8318 2394-3327 |
| DOI: | 10.56093/ijans.v90i2.98781 |
| Popis: | In piggery, birth weight and body weight remains most vital economic trait as they directly influence on the production performance of the farm. Implementing the genomic selection would pay way for rapid genetic gain along with increased accuracy than conventional breeding. Prior to genomic selection, genome wide association study (GWAS) has to be conducted in order to find informative SNPs associated with the traits of interest in a given population. Under this study 96 crossbred pigs were genotyped using double digest genotype by sequencing (GBS) technique using Hiseq platform. Raw FASTQ data were processed using dDOCENT Pipeline on Reference based method and variants were called using Free Bayes (version 1.1.0-3). Using Plink (v1.09b), variants having MAF>0.01, HWE80% were filtered out and 20,467 SNPs were retained after quality control, for ascertaining GWAS in 96 pigs. Before conducting association studies, the data were adjusted for significant nongenetic factors affecting the traits of interest. GWAS was performed using Plink software (v1.9b) identified 9, 11, 12, 23, 28, 24, 30, 33 and 42 SNPs significantly (adjusted P |
| Databáze: | Directory of Open Access Journals |
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