Innovative, Non-stirred Bioreactors in Scales from Milliliters up to 1000 Liters for Suspension Cultures of Cells using Disposable Bags and Containers – A Swiss Contribution
| Autor: | Sören Werner, David Hacker, Lucia Baldi, Rolf Tanner, Markus Kühner, Gilles Broccard, Cedric Bürkie, Stephanie Tissot, Matthieu Stettler, Xiaowei Zhang, Maria De Jesus, Dieter Eibl, Marcel Röll, Christine Lettenbauer, Regine Eibl, Florian M. Wurm |
|---|---|
| Jazyk: | German<br />English<br />French |
| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | CHIMIA, Vol 64, Iss 11 (2010) |
| Druh dokumentu: | article |
| ISSN: | 0009-4293 2673-2424 |
| DOI: | 10.2533/chimia.2010.819 |
| Popis: | Innovative mixing principles in bioreactors, for example using the rocking of a platform to induce a backwards and forwards 'wave' , or using orbital shaking to generate a 'wave' that runs round in a cylindrical container, have proved to be successful for the suspension cultures of cells, especially when combined with disposable materials. This article presents an overview of the engineering characteristics when these new principles are applied in bioreactors, and case studies covering scales of operation from milliliters to 1000 liters. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|