Tissue-level alveolar epithelium model for recapitulating SARS-CoV-2 infection and cellular plasticity

Autor: Jia-Wei Yang, Yu-Rou Lin, Ying-Ling Chu, Johnson H. Y. Chung, Huai-En Lu, Guan-Yu Chen
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Druh dokumentu: article
ISSN: 2399-3642
DOI: 10.1038/s42003-022-03026-3
Popis: Yang et al. present an alveolar cell culture method that utilizes primary human alveolar epithelial cells, culturing cells in a small-molecule cocktail supplemented media. The authors show that the longevity of the primary cells culture can be expanded, and study human alveolar development, infection, injury repair, while demonstrating its use for SARS-CoV-2 infection.
Databáze: Directory of Open Access Journals
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