Autor: |
Rosanna Squitti, Carlo C. Quattrocchi, Gloria Dal Forno, Piero Antuono, David R. Wekstein, Concetta R. Capo, Carlo Salustri, Paolo M. Rossini |
Jazyk: |
angličtina |
Rok vydání: |
2006 |
Předmět: |
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Zdroj: |
Biomarker Insights, Vol 1, Pp 205-213 (2006) |
Druh dokumentu: |
article |
ISSN: |
1177-2719 |
Popis: |
A dysfunction in copper homeostasis seems to occur in Alzheimer's disease (AD). We previously evidenced that an excess of non-ceruloplasmin-copper (NCC) correlated with the main functional, anatomical as well as cerebrospinal markers of the disease. Aim of our study was to investigate ceruloplasmin isoforms as potential actors in this AD copper dysfunction. Our data show that AD patients have ceruloplasmin fragments of low molecular weight ( |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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