Non-altered incretin secretion in women with impaired fasting plasma glucose in the early stage of pregnancy: a case control study

Autor:	Ondrej Krystynik, David Karasek, Michal Kahle, Veronika Kubickova, Dominika Macakova, Lubica Cibickova, Milos Mraz, Martin Haluzik
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Gestational diabetes Glucagon-like peptide 1 Glucose-dependent insulinotropic peptide Glucagon Meal test Nutritional diseases. Deficiency diseases RC620-627
Zdroj:	Diabetology & Metabolic Syndrome, Vol 15, Iss 1, Pp 1-9 (2023)
Druh dokumentu:	article
ISSN:	1758-5996
DOI:	10.1186/s13098-023-00981-7
Popis:	Abstract Backgrounds Glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) may be involved in pathogenesis of gestational diabetes mellitus (GDM). The aim was to compare GLP-1 and GIP production in fasting state and during 3 h mixed meal tolerance test (MMTT) measured by mean area under the curve (AUC) between pregnant women with normal and impaired fasting glucose in an early phase of pregnancy, and healthy non-pregnant controls. Methods This study was undertaken as a case–control study. Repeated measurement of fasting plasma glucose ≥ 5.1 mmol/L and
Databáze:	Directory of Open Access Journals
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