Ovarian volume, not follicle count, is independently associated with androgens in patients with polycystic ovary syndrome

Autor: Asieh Mansour, Amir Pejman Hashemi Taheri, Behnaz Moradi, Mohammad Reza Mohajeri-Tehrani, Mostafa Qorbani, Sahar Ghorbani Pashakolaee, Milad Sanginabadi, Sayed Mahmoud Sajjadi-Jazi
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMC Endocrine Disorders, Vol 22, Iss 1, Pp 1-9 (2022)
Druh dokumentu: article
ISSN: 1472-6823
DOI: 10.1186/s12902-022-01224-y
Popis: Abstract Background Polycystic ovary syndrome (PCOS) is diagnosed based on chronic anovulation, androgen excess (clinical and/or biochemical), and polycystic ovaries in ultrasound. The aim of the present study was to evaluate which parameters in the transvaginal ultrasound (TVUS) of ovaries could be better associated with concurrent hormonal imbalance in the women with PCOS. Methods Using a cross-sectional design, this study focused on 61 subjects (18–40 years) with PCOS. Patients were recruited at three academic hospitals during the 2017–2019 period. PCOS was defined according to the Rotterdam criteria. The association of ovarian morphology with hormonal and metabolic feature was investigated using linear regression models, adjusted for a set of possible confounding variables including age, mensuration status and body mass index (BMI). Results The mean volume of both ovaries was positively associated with the total testosterone level (β = 0.025, P value
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