Correlation Between TCF7+ T Cells and Prognosis of Patients With Oral Squamous Cell Carcinoma

Autor: Haixu Rong, Tingting Cai, Yu Peng, Xiaojuan Wang, Tianjun Lan, Zhanpeng Ou, Ling Qiu, Qunxing Li, Lizao Zhang, Fan Wu, Hsinyu Lin, Siqi Ren, Zitian Li, Song Fan, Jinsong Li
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Frontiers in Oncology, Vol 12 (2022)
Druh dokumentu: article
ISSN: 2234-943X
DOI: 10.3389/fonc.2022.782058
Popis: ObjectiveTo investigate whether TCF7+ T cells constitute an important factor to improve the existing postoperative prediction model for patients with oral squamous cell carcinoma.MethodTCF7+ T cells were detected in the tissues of 167 OSCC patients by multiplex immunofluorescence. The percentage of TCF7+ T cells was transformed into a dichotomous variable, combined with the clinicopathological data for the OSCC patients, and then subjected to univariate and multivariate analyses. The derived independent predictors were then incorporated into risk models to analyze their relationship with the prognosis of patients.ResultsThe high TCF7+ group had a better prognosis than the low TCF7+ group (OS: p
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