Hepato‐splanchnic fluxes during exercise in patients with cirrhosis—a pilot study

Autor: Stefanos Volianitis, Niels H. Secher, Otto Clemmesen, Peter Ott, Henning Bay Nielsen
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Physiological Reports, Vol 12, Iss 18, Pp n/a-n/a (2024)
Druh dokumentu: article
ISSN: 2051-817X
DOI: 10.14814/phy2.16162
Popis: Abstract In cirrhotic patients, compromised hepatocyte function combined with disturbed hepatic blood flow could affect hepato‐splanchnic substrate and metabolite fluxes and exacerbate fatigue during exercise. Eight cirrhotic patients performed incremental cycling trials (3 × 10 min; at light (28 [19–37] W; median with range), moderate (55 [41–69] W), and vigorous (76 [50–102] W) intensity). Heart rate increased from 68 (62–74) at rest to 95 (90–100), 114 (108–120), and 140 (134–146) beats/min (P
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