Recognising Nail Changes Induced by Chemotherapy with Taxane-based Regimens and their Dermoscopic Confirmation: A Prospective Observational Study from Northern India
| Autor: | Rupinder Walia, Shivali Aggarwal, Dimple Chopra, Shayna Aulakh, Anushruti Aggarwal, Sharang Gupta, Preeyati |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Journal of Clinical and Diagnostic Research, Vol 16, Iss 9, Pp WC01-WC04 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2249-782X 0973-709X |
| DOI: | 10.7860/JCDR/2022/55977.16870 |
| Popis: | Introduction: Taxanes are chemotherapeutic agents used in a variety of solid tumours. They are known to cause cutaneous as well as nail changes which are temporally associated with intake of drug. Nail involvement is reported in literature from some parts of the world. Aim: To study the pattern of nail changes occurring due to taxane-based chemotherapy regimens in patients suffering from malignancies. Materials and Methods: This prospective observational study was carried out in a tertiary care hospital in GMC, Patiala, Punjab, India from October 2020 to September 2021. A total of 160 adult patients undergoing cancer chemotherapy with taxanes were included in the study. After taking detailed history, nail changes were examined and confirmed by dermoscopy. The data was analysed using Epi Info 7 by Centers for Disease Control and Prevention (CDC) and Chi-square test was used to calculate the p-value. A p-value |
| Databáze: | Directory of Open Access Journals |
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