Effect of Magnesium Sulphate with Bupivacaine in Ultrasound-guided Transversus Abdominis Plane Block in patients undergoing Total Abdominal Hysterectomy
| Autor: | Nikita Gurung, Navindra Raj Bista, Anil Shrestha, Bigen Man Shakya, Binita Acharya |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Journal of Karnali Academy of Health Sciences, Vol 4, Iss 2 (2021) |
| Druh dokumentu: | article |
| ISSN: | 2616-0064 2676-1327 |
| Popis: | Background: Transversus abdominis plane block is a valuable component of multimodal analgesia regimen. Magnesium sulphate has been shown to increase the duration of action of different peripheral nerve blocks. We assessed the efficacy of magnesium sulphate as an adjuvant to bupivacaine in transversus abdominis plane block in patients scheduled for total abdominal hysterectomy under general anaesthesia. Methods: Sixty-six patients undergoing total abdominal hysterectomy under general anaesthesia were divided into two groups. Ultrasound-guided bilateral transversus abdominis plane block was performed in both groups before extubation. Bupivacaine alone group received block with 20ml of 0.25% bupivacaine while Bupivacaine with Magnesium group received block with 20ml of 0.25% bupivacaine with 150mg of magnesium sulphate on each side. Pain scores at 0, 2, 4, 6, 12, and 24 hours postoperatively along with time to first request of analgesia, total consumption of fentanyl, and incidence of nausea or vomiting were noted. Results: Group BM showed significantly lower pain scores at 4 and 6 hours (p=0.001 and 0.017 respectively). Time to first request of analgesia was significantly more in Group BM [285 minutes (85, 370) vs. 75 minutes (52.5, 150), (p |
| Databáze: | Directory of Open Access Journals |
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