Effect of Royal Jelly on Blood Glucose and Lipids in Streptozotocin Induced Type 1 Diabetic Rats
Autor: | Mojtaba Asgari, Masoumeh Asle-Rousta, Mohammad Sofiabadi |
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Jazyk: | perština |
Rok vydání: | 2017 |
Předmět: | |
Zdroj: | Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, Vol 20, Iss 5, Pp 48-56 (2017) |
Druh dokumentu: | article |
ISSN: | 1735-5338 2008-644X |
Popis: | Abstract Background: Diabetes is the most common endocrine disorder that leads to hyperglycemia and hyperlipidemia. Royal jelly is as a bee-collected natural product has diverse biological properties and that is rich in natural antioxidants. The aim of this study was to investigate the effects of royal jelly on serum glucose and lipids profile in streptozotocin induced type 1 diabetic rats. Materials and Methods: In this experimental study, 40male Wistar rats were divided into 5 groups(8 in each): control, diabetic rats, Glibenclamide, and two groups of royal jelly- treated diabetic. Diabetes was induced in the rats by injection of streptozotocin (60 mg/kg b.w) intraperitoneally. The royal jelly was gavaged at doses of 100 and 200 mg/kg after streptozotocin injection for30 days. At the end of this period, levels of glucose, cholesterol, triglyceride, LDL and HDL in serum were measured. Results: Royal jelly and Glibenclamide significantly decreased the levels of glucose, cholesterol, triglyceride and LDL in diabetic rats (p |
Databáze: | Directory of Open Access Journals |
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