| Autor: |
Julie Wulf Christensen, Karin Folmer Thøgersen, Lars Thorbjørn Jensen, Martin Krakauer, Bent Kristensen, Finn Noe Bennedbæk, Bo Zerahn |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Endocrine Connections, Vol 11, Iss 3, Pp 1-10 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2049-3614 |
| DOI: |
10.1530/EC-21-0630 |
| Popis: |
Objective: The extent of symptoms due to primary hyperparathyroidism (PHPT) depends on the population being studied. PHPT is mainly discovered incidentally through routine laboratory findings. Less is known about patient-experienced imp rovement following successful parathyroidectomy. The aim of our study was to asses s the changes in the quality of life (QoL) after successful surgery using an SF-36 q uestionnaire. Design: This is a prospective cohort study based on questionnaires. Methods: Forty consecutive patients diagnosed with PHPT were prospectiv ely administered an SF-36 questionnaire before and 6 months after s uccessful parathyroidectomy. A subgroup of 18 patients answered the quest ionnaire at 1 and 3 months after surgery. Successful surgery was based on biochem istry and pathology reports as confirmed by an endocrinologist. Results of each SF-3 6 subcategory were compared to the results at baseline in order to detect changes in patient-reported QoL after successful surgery. Results: There were significant improvements in six of eight SF-36 subca tegories: vitality (P = 0.0001), physical functioning (P = 0.04), general health perception (P = 0.004), physical role functioning (P = 0.04), social role functioning (P = 0.004), and mental health perception (P = 0.0001). Changes appeared within a month after surgery with no further significant changes at later time points. Conclusions: Parathyroidectomy significantly improves QoL as measured by a d ecrease in SF-36 scores as early as 1 month after successful parathyroi dectomy. The SF-36 QoL questionnaire is suitable for monitoring changes in patient wel l-being after successful parathyroidectomy. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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