Efficacy and Safety of the Modified Cretan Protocol in Patients with Post-LASIK Ectasia

Autor: Burak Tanrıverdi, Özge Saraç, Berke Temel, Esra Dağ Şeker, Nurullah Çağıl
Jazyk: English<br />Turkish
Rok vydání: 2024
Předmět:
Zdroj: Türk Oftalmoloji Dergisi, Vol 54, Iss 3, Pp 120-126 (2024)
Druh dokumentu: article
ISSN: 1300-0659
2147-2661
DOI: 10.4274/tjo.galenos.2024.82342
Popis: Objectives: To investigate the clinical efficacy and safety of the modified Cretan protocol in patients with post-laser in situ keratomileusis ectasia (PLE). Materials and Methods: In this retrospective study, 26 eyes of 16 patients with PLE were treated with the modified Cretan protocol (combined transepithelial phototherapeutic keratectomy and accelerated corneal collagen cross-linking). Visual, refractive, tomographic, and aberrometric outcomes and point spread function (PSF) were recorded preoperatively and at 6, 12, and 24 months after treatment. Results: Both uncorrected and best corrected visual acuity were stable at 24 months postoperatively compared to baseline (from 0.89±0.36 to 0.79±0.33 logarithm of the minimum angle of resolution [LogMAR] and 0.31±0.25 to 0.24±0.19 LogMAR, respectively, p>0.05 for all values). The mean K1, K2, Kmean, thinnest corneal thickness, and spherical aberration at baseline were 45.76±5.75 diopters (D), 48.62±6.17 D, 47.13±5.89 D, 433.16±56.86 µm, and -0.21±0.63 µm respectively. These values were reduced to 42.86±6.34 D, 45.92±6.74 D, 44.21±6.4 D, 391.07±54.76 µm, and -0.51±0.58 µm at 24 months postoperatively (p0.05 for all variables), while anterior and posterior elevation were significantly improved at 24 months postoperatively (p
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