Nocardia Infections in the Immunocompromised Host: A Case Series and Literature Review

Autor: Emanuele Palomba, Arianna Liparoti, Anna Tonizzo, Valeria Castelli, Laura Alagna, Giorgio Bozzi, Riccardo Ungaro, Antonio Muscatello, Andrea Gori, Alessandra Bandera
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Microorganisms, Vol 10, Iss 6, p 1120 (2022)
Druh dokumentu: article
ISSN: 2076-2607
DOI: 10.3390/microorganisms10061120
Popis: Nocardia is primarily considered an opportunistic pathogen and affects patients with impaired immune systems, solid-organ transplant recipients (SOTRs), and patients with haematologic malignancies. We present the cases of six patients diagnosed with nocardiosis at our center in the last two years, describing the various predisposing conditions alongside the clinical manifestation, the diagnostic workup, and the treatment course. Moreover, we propose a brief literature review on Nocardia infections in the immunocompromised host, focusing on SOTRs and haematopoietic stem cell transplantation recipients and highlighting risk factors, clinical presentations, the diagnostic tools available, and current treatment and prophylaxis guidelines.
Databáze: Directory of Open Access Journals