Bile acids. OV. 2,2-Dimethoxypropane: an esterifying agent preferred to diazomethane for chenodeoxycholic acid.

Autor: R Shaw, W H Elliott
Jazyk: angličtina
Rok vydání: 1978
Předmět:
Zdroj: Journal of Lipid Research, Vol 19, Iss 6, Pp 783-787 (1978)
Druh dokumentu: article
ISSN: 0022-2275
DOI: 10.1016/S0022-2275(20)41282-9
Popis: Artifacts formed by methylation of chenodeoxycholic acid with diazomethane are identical to the synthetic 3alpha- and 7 alpha-monomethyl ethers of methyl chenodeoxycholate. The extent of formation of these artifacts with time has been studied. No detectable artifacts were found with 2,2-dimethoxypropane as the methylating agent.
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